In COVID-19, therapeutic vs. prophylactic anticoagulation did not improve clinical outcomes and increased bleeding

Ann Intern Med. 2021 Oct;174(10):JC112. doi: 10.7326/ACPJ202110190-112. Epub 2021 Oct 5.

Abstract

Lopes RD, de Barros E Silva PG, Furtado RH, et al. Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial. Lancet. 2021;397:2253-63. 34097856.

Publication types

  • Comment

MeSH terms

  • Anticoagulants
  • COVID-19*
  • Hemorrhage
  • Hospitalization
  • Humans
  • SARS-CoV-2

Substances

  • Anticoagulants