Vonoprazan-containing therapy has an H pylori eradication rate >90% and increases eradication vs. standard triple therapy

Ann Intern Med. 2021 Oct;174(10):JC117. doi: 10.7326/ACPJ202110190-117. Epub 2021 Oct 5.

Abstract

Rokkas T, Gisbert JP, Malfertheiner P, et al. Comparative effectiveness of multiple different first-line treatment regimens for Helicobacter pylori infection: a network meta-analysis. Gastroenterology. 2021;161:495-507. 33839101.

Publication types

  • Comment

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Clarithromycin / therapeutic use
  • Drug Therapy, Combination
  • Helicobacter Infections* / drug therapy
  • Helicobacter pylori*
  • Humans
  • Proton Pump Inhibitors / therapeutic use
  • Pyrroles
  • Sulfonamides

Substances

  • 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
  • Anti-Bacterial Agents
  • Proton Pump Inhibitors
  • Pyrroles
  • Sulfonamides
  • Clarithromycin