A Novel Mechanism Underlying Inflammatory Smooth Muscle Phenotype in Abdominal Aortic Aneurysm

Circ Res. 2021 Oct 29;129(10):e202-e214. doi: 10.1161/CIRCRESAHA.121.319374. Epub 2021 Sep 23.

Dunpeng Cai^{1

2}, Chenming Sun³, Gui Zhang³, Xingyi Que¹, Ken Fujise⁴, Neal L Weintraub^{5

6}, Shi-You Chen^{1

2

3}

¹ Departments of Surgery (D.C., X.Q., S.-Y.C.), University of Missouri School of Medicine, Columbia.
² Department of Medical Pharmacology & Physiology (D.C., S.-Y.C.), University of Missouri School of Medicine, Columbia.
³ Department of Physiology & Pharmacology, University of Georgia, Athens (C.S., G.Z., S.-Y.C.).
⁴ Harborview Medical Center, Department of Medicine, University of Washington, Seattle (K.F.).
⁵ Department of Medicine (N.L.W.).
⁶ Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, GA (N.L.W.).

Abstract

[Figure: see text].

Keywords: angiotensin II; aortic aneurysm, abdominal; interleukin; matrix metalloproteinase; phenotype.