Clinical InvestigationMechanical Tricuspid Prosthetic Valve FunctionMultiparametric Approach for the Assessment of Mechanical Prosthetic Tricuspid Leaflet Function
Section snippets
Methods
The study was conducted at the King Faisal Specialist Hospital & Research Center, from which all patients were included. The study was approved by the institutional review board under the Heart Center valve registry. No industry support was provided.
Patient Characteristics
Patient characteristics in the control and leaflet dysfunction groups are listed in Table 1. At a mean follow-up of 53 ± 56 months (range, 3–249 months), 21 episodes of MPTV leaflet dysfunction were detected in 12 of 68 patients (18%). Most patients (76%) were women, and none was pregnant. Seven patients experienced single episodes of leaflet dysfunction, two patients experienced two episodes each, two patients experienced three episodes each, and one patient experienced four episodes. In the
Discussion
This report represents the largest and most detailed analysis to date that aimed to identify the echocardiographic parameters associated with normal as well as abnormal MPTV leaflet function due to valve thrombosis. We suggest that a comprehensive transthoracic echocardiographic approach incorporating 2D, color, and spectral Doppler imaging is essential for the optimal assessment of MPTV function. On the basis of comparison with normally functioning prostheses, we propose cutoff values for
Conclusion
This study represents the first comprehensive echocardiographic assessment of leaflet dysfunction due to valve thrombosis in patients with bileaflet MPTVs. Because of the small sample size and retrospective nature of our study, our findings require further confirmation. We suggest that MPTV dysfunction can be identified on TTE using a multiparametric approach, and we propose an algorithm integrating several transthoracic echocardiographic parameters to distinguish normal from abnormal MPTV
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Conflicts of Interest: None.