Adenosine revives catheter-induced mechanical blocks in radiofrequency ablation

J Cardiovasc Electrophysiol. 2021 Nov;32(11):3103-3106. doi: 10.1111/jce.15235. Epub 2021 Sep 7.

Abstract

Adenosine can hyperpolarize the atrial action potential, which helps rapidly re-establish the membrane potential in ablated sites and unmask "dormant conduction." It has been reported that pharmacological agents, including adenosine, were unable to revive traumatized tissues. We present the first case of the catheter-induced mechanical block ("bump" phenomenon) that was unmasked with adenosine administration in the working myocardium of the superior vena cava. This result may be because, unlike before, we could determine the force of contact between the tip of the ablation catheter and the myocardial tissue. This case suggests the clinical usefulness of adenosine for unmasking bumped sites.

Keywords: adenosine; atrial fibrillation; catheter-induced mechanical trauma; dormant conduction; superior vena cava isolation.

Publication types

  • Case Reports

MeSH terms

  • Adenosine
  • Atrial Fibrillation* / diagnosis
  • Atrial Fibrillation* / surgery
  • Catheter Ablation* / adverse effects
  • Catheters
  • Humans
  • Pulmonary Veins* / surgery
  • Treatment Outcome
  • Vena Cava, Superior

Substances

  • Adenosine