Congenital: FontanDiastolic inflow is associated with inefficient ventricular flow dynamics in Fontan patients
Read at the 100th Annual Meeting of The American Association for Thoracic Surgery: A Virtual Learning Experience, May 22-23, 2020.
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Graphical abstract
Flow component analysis by 4D-flow CMR demonstrates inefficient diastolic inflow partitioning in patients with HLHS and HRHS compared with biventricular control patients as defined by decreased direct flow and increased residual volume.
Key Words
4D-flow cardiac MRI
hypoplastic left heart syndrome
hypoplastic right heart syndrome
post-Fontan physiology
single ventricle congenital heart disease
Abbreviations and Acronyms
CMR
cardiac magnetic resonance
4D
4-dimensional
HLHS
hypoplastic left heart syndrome
HRHS
hypoplastic right heart syndrome
MRI
magnetic resonance imaging
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Funding source: Rady Family and Jayden DeLuca Foundations.
The Institutional Review Board of the University of Colorado School of Medicine approved the study protocol and publication of data (Institutional Review Board protocol no. 19-1420; date of approval: June 20, 2019). The patients provided informed written consent for the publication of the study data.
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