Long-term (≥15 years) Follow-up of Percutaneous Coronary Intervention of Unprotected Left Main (From the GRAVITY Registry)
Section snippets
Methods
GRAVITY is a multicenter retrospective registry including consecutive patients undergoing unprotected left main PCI between June 2002 and 2005 at 9 European centers). The study complies with the Declaration of Helsinki: all patients provided informed consent for inclusion in the registry, and institutional review board approval was obtained at each center.
Cardiovascular risk factors, clinical presentation, angiographic features, use of intravascular imaging, bifurcation technique details,
Results
General characteristics of overall cohort are reported in Table 1. The mean age at the enrollment was 66.6 years (SD 11.7), 71.5% of patients were male and hypertension was the most common cardiovascular risk factor (81.9%), while 34.1% of patients were active smokers. Admission diagnosis was STEMI in 14.4% of the cases, while mean creatinine at admission was 1.2 mg/dl (SD 0.8). At the time of discharge mean LVEF was 48% (SD 16.8) and dual antiplatelet therapy (DAPT) was prescribed in 88.1% of
Discussion
The main findings of this multicenter retrospective cohort study assessing the long-term outcome of PCI on ULMCA are:
- 1)
Less than 20% of patients with PCI on ULMCA died for CV reasons at 15 years
- 2)
A severe systolic dysfunction at discharge (LVEF < 35%) was the only independent predictor of long-term CV mortality, with no other clinical, angiographic or procedural factors affecting CV outcome.
- 3)
Most of re-PCI on ULMCA occurred during the first year and were predicted by clinical presentation and
Disclosure
Nothing to declare.
Declaration of Competing Interests
The authors declare that they have no known competing financial interests or personal relations that could have appeared to influence the work reported in this study.
Acknowledgment
Nothing to declare.
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