In older adults with subclinical hypothyroidism, levothyroxine therapy did not reduce depressive symptoms at 12 mo

Ann Intern Med. 2021 Jul;174(7):JC81. doi: 10.7326/ACPJ202107200-081. Epub 2021 Jul 6.

Abstract

Wildisen L, Feller M, Del Giovane C, et al. Effect of levothyroxine therapy on the development of depressive symptoms in older adults with subclinical hypothyroidism: an ancillary study of a randomized clinical trial. JAMA Netw Open. 2021;4:e2036645. 33566107.

Publication types

  • Comment

MeSH terms

  • Aged
  • Depression / drug therapy
  • Humans
  • Hypothyroidism* / complications
  • Hypothyroidism* / drug therapy
  • Thyroxine* / therapeutic use

Substances

  • Thyroxine