First lung and kidney multi-organ transplant following COVID-19 Infection

Brandon A Guenthart; Aravind Krishnan; Aiman Alassar; Jai Madhok; Monika Kakol; Shari Miller; Sheela Pai Cole; Vidya K Rao; Natalia Martinez Acero; Charles C Hill; Cindy Cheung; Ethan C Jackson; Igor Feinstein; Albert H Tsai; Joshua J Mooney; Thomas Pham; Irmina A Elliott; Douglas Z Liou; Saverio La Francesca; Yasuhiro Shudo; William Hiesinger; John W MacArthur; Nivaz Brar; Gerald J Berry; Matthew B McCarra; Tushar J Desai; Gundeep S Dhillon; Y Joseph Woo

doi:10.1016/j.healun.2021.02.015

First lung and kidney multi-organ transplant following COVID-19 Infection

J Heart Lung Transplant. 2021 Aug;40(8):856-859. doi: 10.1016/j.healun.2021.02.015. Epub 2021 May 2.

Authors

Brandon A Guenthart¹, Aravind Krishnan¹, Aiman Alassar¹, Jai Madhok², Monika Kakol³, Shari Miller¹, Sheela Pai Cole², Vidya K Rao², Natalia Martinez Acero², Charles C Hill², Cindy Cheung², Ethan C Jackson², Igor Feinstein², Albert H Tsai², Joshua J Mooney³, Thomas Pham⁴, Irmina A Elliott¹, Douglas Z Liou¹, Saverio La Francesca¹, Yasuhiro Shudo¹, William Hiesinger¹, John W MacArthur¹, Nivaz Brar⁵, Gerald J Berry⁵, Matthew B McCarra⁶, Tushar J Desai⁶, Gundeep S Dhillon³, Y Joseph Woo⁷

Affiliations

¹ Department of Cardiothoracic Surgery, Stanford University, Stanford, CA.
² Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University, Stanford, CA.
³ Department of Medicine, Division of Pulmonary, Allergy, and Critical Care, Stanford University, Stanford, CA.
⁴ Department of Surgery, Division of Abdominal Transplantation, Stanford University, Stanford, CA.
⁵ Department of Pathology, Stanford University, Stanford, CA.
⁶ Department of Medicine, Division of Pulmonary, Allergy, and Critical Care, Stanford University, Stanford, CA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA.
⁷ Department of Cardiothoracic Surgery, Stanford University, Stanford, CA. Electronic address: joswoo@stanford.edu.

Abstract

As the world responds to the global crisis of the COVID-19 pandemic an increasing number of patients are experiencing increased morbidity as a result of multi-organ involvement. Of these, a small proportion will progress to end-stage lung disease, become dialysis dependent, or both. Herein, we describe the first reported case of a successful combined lung and kidney transplantation in a patient with COVID-19. Lung transplantation, isolated or combined with other organs, is feasible and should be considered for select patients impacted by this deadly disease.

Keywords: COVID-19, lung transplant; ECMO; kidney transplant; multi-organ transplant.

Publication types

Case Reports
Letter

MeSH terms

Acute Kidney Injury / etiology*
Acute Kidney Injury / surgery*
COVID-19 / complications*
COVID-19 / surgery*
Humans
Kidney Transplantation*
Lung Transplantation*
Male
Middle Aged
Respiratory Distress Syndrome / etiology*
Respiratory Distress Syndrome / surgery*