State-of-the-Art ReviewMultimodality Imaging Assessment of Myocardial Fibrosis
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Central Illustration
Key Words
cardiac computed tomography
cardiac magnetic resonance
late gadolinium enhancement
myocardial fibrosis
nuclear imaging
T1 mapping
Abbreviations and Acronyms
CMR
cardiac magnetic resonance
CT
computed tomography
CT-DE
computed tomographic delayed enhancement
DCM
dilated cardiomyopathy
ECM
extracellular matrix
ECV
extracellular volume
HCM
hypertrophic cardiomyopathy
IR
inversion recovery
LGE
late gadolinium enhancement
LL
Look-Locker
LV
left ventricular
MI
myocardial infarction
MOLLI
modified Look-Locker imaging
PET
positron-emission tomography
PSIR
phase-sensitive inversion recovery
PTI
perfusable tissue index
SPECT
single photon-emission computed tomography
SR
saturation recovery
T-CRIP
99mTc-labeled cyanine-5.5 Arg-Gly-Asp imaging peptide
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Erik Schelbert, MD, served as Guest Editor for this paper.
The authors attest they are in compliance with human studies committees and animal welfare regulations of the authors’ institutions and Food and Drug Administration guidelines, including patient consent where appropriate. For more information, visit the Author Center.
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Drs. Gupta and Ge contributed equally to this work and are joint first authors.
© 2021 by the American College of Cardiology Foundation. Published by Elsevier.