In statin-treated patients at high CV risk, adding omega-3 fatty acids vs. corn oil to usual care did not reduce MACE

Ann Intern Med. 2021 Apr;174(4):JC40. doi: 10.7326/ACPJ202104200-040. Epub 2021 Apr 6.

Abstract

Nicholls SJ, Lincoff AM, Garcia M, et al. Effect of high-dose omega-3 fatty acids vs corn oil on major adverse cardiovascular events in patients at high cardiovascular risk: the STRENGTH randomized clinical trial. JAMA. 2020;324:2268-80. 33190147.

Keywords: Cardiovascular diseases; Corn oil; Docosahexaenoic acids; Eicosapentaenoic acid.

Publication types

  • Comment

MeSH terms

  • Cardiovascular Diseases* / prevention & control
  • Corn Oil
  • Fatty Acids, Omega-3*
  • Heart Disease Risk Factors
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors* / adverse effects
  • Risk Factors

Substances

  • Fatty Acids, Omega-3
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Corn Oil