In Vitro Cell Selectivity of Reversible and Irreversible: Electroporation in Cardiac Tissue

Circ Arrhythm Electrophysiol. 2021 Apr;14(4):e008817. doi: 10.1161/CIRCEP.120.008817. Epub 2021 Mar 17.

Authors

David W Hunter¹, Geran Kostecki², Jeffrey M Fish³, James A Jensen³, Harikrishna Tandri¹

Affiliations

¹ Department of Medicine (D.W.H., H.T.), The Johns Hopkins University, Baltimore, MD.
² Department of Biomedical Engineering (G.K.), The Johns Hopkins University, Baltimore, MD.
³ Abbott Laboratories, St. Paul, MN (J.M.F., J.A.J.).

PMID: 33729827
DOI: 10.1161/CIRCEP.120.008817

Abstract

[Figure: see text].

Keywords: atrial fibrillation; catheter ablation; electrode; electroporation; pulmonary vein.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Action Potentials
Animals
Animals, Newborn
Cell Death
Cells, Cultured
Cerebral Cortex / pathology
Electrodes
Electroporation* / instrumentation
Esophagus / pathology
Myocytes, Cardiac / pathology*
Myocytes, Smooth Muscle / pathology
Neurons / pathology
Pilot Projects
Pulmonary Veins / pathology
Pulmonary Veins / physiopathology
Pulmonary Veins / surgery*
Rats
Rats, Sprague-Dawley
Voltage-Sensitive Dye Imaging