Racial differences in management and outcomes of acute myocardial infarction during COVID-19 pandemic

Heart. 2021 May;107(9):734-740. doi: 10.1136/heartjnl-2020-318356. Epub 2021 Mar 8.

Abstract

Objective: There are concerns that healthcare and outcomes of black, Asian and minority ethnic (BAME) communities are disproportionately impacted by the COVID-19 pandemic. We investigated admission rates, treatment and mortality of BAME with acute myocardial infarction (AMI) during COVID-19.

Methods: Using multisource national healthcare records, patients hospitalised with AMI in England during 1 February-27 May 2020 were included in the COVID-19 group, whereas patients admitted during the same period in the previous three consecutive years were included in a pre-COVID-19 group. Multilevel hierarchical regression analyses were used to quantify the changes in-hospital and 7-day mortality in BAME compared with whites.

Results: Of 73 746 patients, higher proportions of BAME patients (16.7% vs 10.1%) were hospitalised with AMI during the COVID-19 period compared with pre-COVID-19. BAME patients admitted during the COVID-19 period were younger, male and likely to present with ST-elevation acute myocardial infarction. COVID-19 BAME group admitted with non-ST-elevation acute myocardial infarction less frequently received coronary angiography (86.1% vs 90.0%, p<0.001) and had a longer median delay to reperfusion (4.1 hours vs 3.7 hours, p<0.001) compared with whites. BAME had higher in-hospital (OR 1.68, 95% CI 1.27 to 2.28) and 7-day mortality (OR 1.81 95% CI 1.31 to 2.19) during COVID-19 compared with pre-COVID-19 period.

Conclusion: In this multisource linked cohort study, compared with whites, BAME patients had proportionally higher hospitalisation rates with AMI, less frequently received guidelines indicated care and had higher early mortality during COVID-19 period compared with pre-COVID-19 period. There is a need to develop clinical pathways to achieve equity in the management of these vulnerable populations.

Keywords: acute coronary syndrome; health care; outcome assessment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19* / mortality
  • COVID-19* / therapy
  • Coronary Angiography / methods
  • Coronary Angiography / statistics & numerical data
  • Critical Pathways* / organization & administration
  • Critical Pathways* / standards
  • England / epidemiology
  • Female
  • Health Services Needs and Demand
  • Healthcare Disparities* / standards
  • Healthcare Disparities* / statistics & numerical data
  • Hospitalization / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Non-ST Elevated Myocardial Infarction* / ethnology
  • Non-ST Elevated Myocardial Infarction* / therapy
  • Outcome and Process Assessment, Health Care
  • Race Factors
  • SARS-CoV-2
  • ST Elevation Myocardial Infarction* / ethnology
  • ST Elevation Myocardial Infarction* / therapy