Use of ¹¹C-acetate PET imaging in the evaluation of advanced atherogenic lesions

J Nucl Cardiol. 2022 Jun;29(3):1277-1279. doi: 10.1007/s12350-021-02562-5. Epub 2021 Mar 4.

Authors

Victoria Fernández-García^{1

2}, Lisardo Boscá^{3

4}

Affiliations

¹ Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), Madrid, Spain.
² Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.
³ Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), Madrid, Spain. lbosca@iib.uam.es.
⁴ Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain. lbosca@iib.uam.es.

PMID: 33665731
DOI: 10.1007/s12350-021-02562-5

Abstract

The use of ¹¹C-acetate as a PET/CT tracer for atherosclerotic lesions preferentially labels anti-inflammatory/pro-resolution intra-plaque macrophages. An overview of the mechanisms involved in the selective uptake.

© 2021. American Society of Nuclear Cardiology.

Publication types

Editorial
Comment

MeSH terms

Acetates
Atherosclerosis* / diagnostic imaging
Humans
Plaque, Atherosclerotic* / diagnostic imaging
Positron Emission Tomography Computed Tomography / methods
Positron-Emission Tomography

Substances

Acetates