Patient first versus computed tomography first strategy in testing for stable coronary artery disease: dispelling the prevailing myths and biases

J Nucl Cardiol. 2021 Apr;28(2):735-740. doi: 10.1007/s12350-020-02519-0. Epub 2021 Jan 28.

Abstract

We advocate an evidence-based discussion for a patient first philosophy when considering "the right test for the right patient." Numerous test options exist for the evaluation of symptoms of possible stable ischemic heart disease. Major guidelines have traditionally focused on functional testing with or without imaging to clarify symptoms, diagnose ischemia, stratify prognosis, and guide management. Recently, industry advocates have emphasized modality-specific approaches such as computed tomography (CT First) as an initial test strategy for possible stable CAD. We review the key evidence to demonstrate that current best practice would focus on a patient first approach rather than a modality-specific approach.

Keywords: CAD < Diseases/processes; CT < Modalities; Echo < Modalities; MPI < Tests; PET < Modalities; SPECT < Modalities.

Publication types

  • Comparative Study
  • Editorial

MeSH terms

  • Computed Tomography Angiography / methods*
  • Coronary Artery Disease / diagnostic imaging*
  • Coronary Artery Disease / therapy
  • Fractional Flow Reserve, Myocardial
  • Humans
  • Percutaneous Coronary Intervention