Abstract
Keywords:
atherosclerosis; cardiovascular disease; cholesterol; drug discovery; macrophages.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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ATP Binding Cassette Transporter 1 / genetics
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ATP Binding Cassette Transporter 1 / metabolism*
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Animals
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Anticholesteremic Agents / pharmacology*
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Aorta / drug effects*
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Aorta / metabolism
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Aorta / pathology
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Aortic Diseases / genetics
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Aortic Diseases / metabolism
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Aortic Diseases / pathology
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Aortic Diseases / prevention & control*
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Atherosclerosis / genetics
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Atherosclerosis / metabolism
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Atherosclerosis / pathology
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Atherosclerosis / prevention & control*
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Benzamides / pharmacology*
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Cholesterol / metabolism*
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Disease Models, Animal
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Female
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Hep G2 Cells
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Humans
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Intestinal Elimination / drug effects
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Liver / drug effects
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Liver / metabolism
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Macrophages / drug effects*
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Macrophages / metabolism
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Male
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Mesocricetus
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Mice
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Mice, Inbred C57BL
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Mice, Knockout, ApoE
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Protein Kinase C / genetics
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Protein Kinase C / metabolism
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RAW 264.7 Cells
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Receptors for Activated C Kinase / genetics
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Receptors for Activated C Kinase / metabolism
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Up-Regulation
Substances
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ABCA1 protein, human
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ABCA1 protein, mouse
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ATP Binding Cassette Transporter 1
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Anticholesteremic Agents
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Benzamides
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Receptors for Activated C Kinase
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Cholesterol
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protein kinase C zeta
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Protein Kinase C