Learning whether to subtract beta-blockers: it's about time

Eur Heart J. 2021 Mar 1;42(9):915-918. doi: 10.1093/eurheartj/ehaa1033.

Abstract

Proposed framework for foundational and provisional secondary prevention therapy over time in low-risk post-MI patients. Foundational therapies should be considered in all patients without contraindications, while provisional therapies should be considered in selected patients with comorbidities or post-infarction complications. The horizontal time axis proposes duration of therapies and timeframes for pharmacotherapeutic re-assessment, and should be responsive to the temporal evolution of post-MI risk and events. ADP, adenosine diphosphate receptor inhibitors; ASA, acetylsalicylic acid; CKD, chronic kidney disease; DM, diabetes mellitus; HTN, hypertension; RAAS, renin-angiotensin-aldosterone system; RCT, randomized controlled trials; TG, triglyceride. *Pending guideline recommendations.

Publication types

  • Editorial
  • Comment

MeSH terms

  • Angiotensin-Converting Enzyme Inhibitors
  • Cohort Studies
  • Denmark
  • Heart Failure*
  • Humans
  • Hypertension* / drug therapy
  • Myocardial Infarction* / drug therapy
  • Renin-Angiotensin System
  • Reperfusion

Substances

  • Angiotensin-Converting Enzyme Inhibitors