Precision medicine for heart failure based on molecular mechanisms: The 2019 ISHR Research Achievement Award Lecture

Seitaro Nomura; Issei Komuro

doi:10.1016/j.yjmcc.2020.11.010

Precision medicine for heart failure based on molecular mechanisms: The 2019 ISHR Research Achievement Award Lecture

J Mol Cell Cardiol. 2021 Mar:152:29-39. doi: 10.1016/j.yjmcc.2020.11.010. Epub 2020 Dec 1.

Authors

Seitaro Nomura¹, Issei Komuro²

Affiliations

¹ Department of Cardiovascular Medicine, The University of Tokyo, Japan.
² Department of Cardiovascular Medicine, The University of Tokyo, Japan. Electronic address: komuro-tky@umin.ac.jp.

PMID: 33275937
DOI: 10.1016/j.yjmcc.2020.11.010

Abstract

Heart failure is a leading cause of death, and the number of patients with heart failure continues to increase worldwide. To realize precision medicine for heart failure, its underlying molecular mechanisms must be elucidated. In this review summarizing the "The Research Achievement Award Lecture" of the 2019 XXIII ISHR World Congress held in Beijing, China, we would like to introduce our approaches for investigating the molecular mechanisms of cardiac hypertrophy, development, and failure, as well as discuss future perspectives.

Publication types

Lecture
Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Awards and Prizes*
Heart Failure / therapy*
Humans
Precision Medicine*