Closing gigantic left atrial appendage using a LAmbre Closure System: First implant experience in North America

J Cardiovasc Electrophysiol. 2021 Jan;32(1):158-161. doi: 10.1111/jce.14811. Epub 2020 Nov 18.

Abstract

Introduction: Despite maturing experience and growing procedural familiarity, there remain challenges in percutaneous left atrial appendage (LAA) closure due to anatomical complexities.

Methods: We report a complex and extremely large LAA that was successfully closed percutaneously using a LAmbre Closure System (Lifetech Scientific Corp.). Cardiac computed tomography angiography demonstrated a gigantic multilobed LAA measuring 48 × 45.3 mm at the level of the ostium that cannot be occluded by the currently approved LAA closure devices in Canada.

Results: The manufacturer custom-made a LAmbre 30/50 mm (lobe/disc) device to fit this patient's LAA according to his CTA, which was successfully deployed under fluoroscopy and transesophageal echocardiogram guidance without procedure-related complications.

Conclusion: The LAmbre device may be considered to close very large LAAs.

Keywords: LAmbre; atrial fibrillation; left atrial appendage closure.

Publication types

  • Case Reports

MeSH terms

  • Atrial Appendage* / diagnostic imaging
  • Atrial Appendage* / surgery
  • Atrial Fibrillation* / diagnostic imaging
  • Atrial Fibrillation* / surgery
  • Canada
  • Cardiac Catheterization / adverse effects
  • Echocardiography, Transesophageal
  • Humans
  • North America
  • Septal Occluder Device*
  • Treatment Outcome