Feasibility and Consistency of Results with Deployment of an In-Line Filter for Exercise-Based Evaluations of Patients With Heart Failure During the Novel Coronavirus Disease-2019 Pandemic

J Card Fail. 2021 Jan;27(1):105-108. doi: 10.1016/j.cardfail.2020.10.005. Epub 2020 Oct 21.

Abstract

Background: Exercise testing plays an important role in evaluating heart failure prognosis and selecting patients for advanced therapeutic interventions. However, concern for severe acute respiratory syndrome novel coronavirus-2 transmission during exercise testing has markedly curtailed performance of exercise testing during the novel coronavirus disease-2019 pandemic.

Methods and results: To examine the feasibility to conducting exercise testing with an in-line filter, 2 healthy volunteer subjects each completed 2 incremental exercise tests, one with discrete stages of increasing resistance and one with a continuous ramp. Each subject performed 1 test with an electrostatic filter in-line with the system measuring gas exchange and air flow, and 1 test without the filter in place. Oxygen uptake and minute ventilation were highly consistent when evaluated with and without use of an electrostatic filter with a >99.9% viral efficiency.

Conclusions: Deployment of a commercially available in-line electrostatic viral filter during cardiopulmonary exercise testing is feasible and provides consistent data compared with testing without a filter.

Keywords: COVID-19; Exercise; Peak VO(2).

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • COVID-19 / epidemiology*
  • COVID-19 / prevention & control*
  • Exercise Test / methods
  • Exercise Test / standards*
  • Feasibility Studies
  • Heart Failure / diagnosis*
  • Heart Failure / epidemiology*
  • Humans
  • Male
  • Oxygen Consumption / physiology
  • Pandemics
  • Pulmonary Gas Exchange / physiology
  • Reproducibility of Results
  • Respiratory Protective Devices / standards*