Potential risk of perioperative thromboembolism in patients with antiphospholipid syndrome who undergo transcatheter aortic valve implantation: A case series

Tomoya Hoshi; Daigo Hiraya; Akira Sato; Masaki Ieda

doi:10.1002/ccd.29300

Potential risk of perioperative thromboembolism in patients with antiphospholipid syndrome who undergo transcatheter aortic valve implantation: A case series

Catheter Cardiovasc Interv. 2021 Aug 1;98(2):E315-E319. doi: 10.1002/ccd.29300. Epub 2020 Sep 25.

Authors

Tomoya Hoshi¹, Daigo Hiraya¹, Akira Sato¹, Masaki Ieda¹

Affiliation

¹ Faculty of Medicine, Department of Cardiology, University of Tsukuba, Tsukuba, Japan.

PMID: 32975371
DOI: 10.1002/ccd.29300

Abstract

Antiphospholipid syndrome (APS) is an autoimmune disease characterized by a positive serum antiphospholipid antibody status. Patients with APS usually have an underlying hypercoagulable state, which can increase the risk of perioperative thromboembolism. We describe three patients with APS who underwent transcatheter aortic valve implantation for symptomatic severe aortic stenosis. Of them, two had complicated cerebrovascular events, and the other had no complications. Careful antithrombotic management is essential to minimize the risk of thromboembolism and bleeding in patients with APS.

Keywords: antiphospholipid syndrome; stroke; transcatheter aortic valve implantation.

Publication types

Case Reports

MeSH terms

Antiphospholipid Syndrome* / complications
Antiphospholipid Syndrome* / diagnosis
Aortic Valve / diagnostic imaging
Aortic Valve / surgery
Aortic Valve Stenosis* / diagnostic imaging
Aortic Valve Stenosis* / surgery
Heart Valve Prosthesis Implantation* / adverse effects
Humans
Risk Factors
Thromboembolism* / diagnosis
Thromboembolism* / etiology
Transcatheter Aortic Valve Replacement* / adverse effects
Treatment Outcome