The rise of pericytes in neurovascular research

J Cereb Blood Flow Metab. 2020 Dec;40(12):2366-2373. doi: 10.1177/0271678X20958497. Epub 2020 Sep 21.

Abstract

The popularity of pericyte research is increasing, and this was not more evident than at the recent 2019 Brain meeting in Yokohama which featured a large number of presentations focused on brain pericyte research, including the Presidential Symposium. In this article, we will provide a history of brain pericyte research, present the results of our analysis showing a substantial increase in brain pericyte research presented at Brain meetings since 2005, suggest reasons for their increased popularity, and comment on what the future holds for brain pericyte research.

Keywords: Alzheimer’s disease; Pericytes; blood–brain barrier; brain; cerebral blood flow; stroke.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alzheimer Disease / metabolism
  • Alzheimer Disease / pathology
  • Blood-Brain Barrier / cytology
  • Blood-Brain Barrier / metabolism*
  • Blood-Brain Barrier / pathology
  • Brain / blood supply*
  • Brain / pathology
  • Brain / physiopathology
  • Cerebrovascular Circulation / physiology
  • Endothelium, Vascular / cytology
  • Endothelium, Vascular / metabolism*
  • Humans
  • Pericytes / metabolism*
  • Pericytes / physiology
  • Publications
  • Research / trends
  • Research Design
  • Stroke / metabolism
  • Stroke / pathology