The Effect of Decongestion on Intrarenal Venous Flow Patterns in Patients With Acute Heart Failure

J Card Fail. 2021 Jan;27(1):29-34. doi: 10.1016/j.cardfail.2020.09.003. Epub 2020 Sep 11.

Abstract

Background: Discontinuous intrarenal venous flow patterns, as assessed by renal Doppler ultrasound examination, are associated with changes in hemodynamics such as volume expansion and poorer diuretic response in patients with heart failure (HF). We aimed to study intrarenal venous and arterial flow patterns after decongestive treatment in patients with acute HF.

Methods and results: Fifteen patients with acute HF were enrolled. Intrarenal venous and arterial flow patterns were assessed at baseline, 1 hour after administration of loop diuretics, at day 2 and day 3. Among patients hospitalized for acute HF, 13 (87%) had a discontinuous venous flow pattern at admission. After decongestive treatment, a significant improvement of the venous impedance index (P = .021) and venous discontinuity index (P = .004) was observed at day 3 compared with baseline. There was no effect on the intrarenal arterial flow patterns.

Conclusions: In patients who exhibit discontinuous renal venous flow patterns hospitalized for decongestive treatment owing to acute HF led to a normalization of intrarenal venous flow to a continuous pattern.

Keywords: Heart failure; decongestion; intrarenal flow.

MeSH terms

  • Diuretics
  • Heart Failure* / diagnostic imaging
  • Heart Failure* / drug therapy
  • Hemodynamics
  • Humans
  • Kidney / diagnostic imaging
  • Sodium Potassium Chloride Symporter Inhibitors
  • Treatment Outcome

Substances

  • Diuretics
  • Sodium Potassium Chloride Symporter Inhibitors