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Kidney injury as post-interventional complication of TAVI

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Abstract

Transcatheter aortic valve implantation (TAVI) is an accepted treatment approach of aortic stenosis. In the beginning, this technique was executed in high-risk patients only. Today, intermediate-risk patients are also amenable for TAVI, as long as the transfemoral approach is chosen. Numerous predictors have been identified that could lead to periprocedural complications and are defined by patient co-morbidities as well as being inherent to the technical approach. Although vascular complications and postinterventional paravalvular regurgitation have been minimized over the past years by revised technologies and techniques, there is a prevailing individual risk brought about by the specific pathophysiology of the cardiorenal syndrome.

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Abbreviations

CM:

Contrast media

TAVI:

Transcatheter aortic valve implantation

eGFR:

Estimated glomerular filtration rate

CKD:

Chronic kidney disease

AKI:

Acute kidney failure

EuroSCORE:

European System for Cardiac Operative Risk Evaluation

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Authors and Affiliations

  1. 5.Medizinische Klinik, Universitätsmedizin Mannheim, Universität Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany

    Michael Morcos

  2. Stoffwechselzentrum Rhein-Pfalz, Belchenstraße 1-5, 69163, Mannheim, Germany

    Michael Morcos

  3. Klinik für Kardiologie, Herz-und Gefäßzentrum, Bad Bevensen, Germany

    Christof Burgdorf, Andrijana Vukadinivikj & Andrew Remppis

  4. Klinik für Innere Medizin III–Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum Des Saarlandes, Homburg/Saar, Germany

    Felix Mahfoud

  5. Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, USA

    Felix Mahfoud

  6. Klinik für Nieren-und Hochdruckkrankheiten, Transplantationszentrum, Klinikum Stuttgart, Stuttgart, Germany

    Joerg Latus & Vedat Schwenger

  7. Charité–Universitätsmedizin Berlin, Institut für Vegetative Physiologie, Charitéplatz 1, 10117, Berlin, Germany

    Pontus B. Persson

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Conflict of interest

Michael Morcos received honoraria from NovoNordisk, BerlinChemie, Sanofi Aventis, Bayer, Astra Zeneca and Amgen. Christof Burgdorf Andrijana Vukadinivikj and Joerg Latus have no conflicts of interest to declare. Felix Mahfoud reports grants from Deutsche Gesellschaft für Kardiologie (DGK), grants from Deutsche Forschungsgemeinschaft (DFG), grants and personal fees from Bayer, grants and personal fees from Boehringer Ingelheim, grants and personal fees from Medtronic, grants and personal fees from ReCor Medical, outside the submitted work. Jörg Latus received honoraria from Amgen, Böhringer Ingelheim, Vifor, Fresenius Medical Care. Pontus P. Persson declares to have received honoraria from Bayer and RenalGuard Solutions regarding renal safety. Vedat Schwenger received honoraria from Fresenius Medical Care and Novartis. Andrew Remppis received honoraria from Novartis, Vifor, BerlinChemie, and RenalGuard Solutions.

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Morcos, M., Burgdorf, C., Vukadinivikj, A. et al. Kidney injury as post-interventional complication of TAVI. Clin Res Cardiol 110, 313–322 (2021). https://doi.org/10.1007/s00392-020-01732-8

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