Impact of COVID-19 outbreak on regional STEMI care in Germany

Clin Res Cardiol. 2020 Dec;109(12):1511-1521. doi: 10.1007/s00392-020-01703-z. Epub 2020 Jul 16.

Abstract

Aims: To assess the impact of the lockdown due to coronavirus disease 2019 (COVID-19) on key quality indicators for the treatment of ST-segment elevation myocardial infarction (STEMI) patients.

Methods: Data were obtained from 41 hospitals participating in the prospective Feedback Intervention and Treatment Times in ST-Elevation Myocardial Infarction (FITT-STEMI) study, including 15,800 patients treated for acute STEMI from January 2017 to the end of March 2020.

Results: There was a 12.6% decrease in the total number of STEMI patients treated at the peak of the pandemic in March 2020 as compared to the mean number treated in the March months of the preceding years. This was accompanied by a significant difference among the modes of admission to hospitals (p = 0.017) with a particular decline in intra-hospital infarctions and transfer patients from other hospitals, while the proportion of patients transported by emergency medical service (EMS) remained stable. In EMS-transported patients, predefined quality indicators, such as percentages of pre-hospital ECGs (both 97%, 95% CI = - 2.2-2.7, p = 0.846), direct transports from the scene to the catheterization laboratory bypassing the emergency department (68% vs. 66%, 95% CI = - 4.9-7.9, p = 0.641), and contact-to-balloon-times of less than or equal to 90 min (58.3% vs. 57.8%, 95%CI = - 6.2-7.2, p = 0.879) were not significantly altered during the COVID-19 crisis, as was in-hospital mortality (9.2% vs. 8.5%, 95% CI = - 3.2-4.5, p = 0.739).

Conclusions: Clinically important indicators for STEMI management were unaffected at the peak of COVID-19, suggesting that the pre-existing logistic structure in the regional STEMI networks preserved high-quality standards even when challenged by a threatening pandemic.

Clinical trial registration: NCT00794001.

Keywords: COVID-19; Contact-to-balloon time; Key quality indicators; Mortality; Percutaneous coronary intervention (PCI); ST-segment elevation myocardial infarction (STEMI).

Publication types

  • Multicenter Study
  • Observational Study

MeSH terms

  • Aged
  • COVID-19* / epidemiology
  • Cardiology Service, Hospital / trends*
  • Cross-Sectional Studies
  • Delivery of Health Care, Integrated / trends*
  • Female
  • Germany / epidemiology
  • Hospital Mortality / trends
  • Hospitalization / trends*
  • Humans
  • Male
  • Middle Aged
  • Outcome and Process Assessment, Health Care / trends*
  • Percutaneous Coronary Intervention / mortality
  • Percutaneous Coronary Intervention / trends*
  • Prospective Studies
  • Quality Indicators, Health Care / trends
  • Regional Health Planning / trends*
  • Registries
  • ST Elevation Myocardial Infarction / diagnosis
  • ST Elevation Myocardial Infarction / mortality
  • ST Elevation Myocardial Infarction / therapy*
  • Time Factors
  • Time-to-Treatment / trends
  • Treatment Outcome

Associated data

  • ClinicalTrials.gov/NCT00794001