Organ-level vascularization: The Mars mission of bioengineering

Boyang Zhang; Milica Radisic

doi:10.1016/j.jtcvs.2019.08.128

Organ-level vascularization: The Mars mission of bioengineering

J Thorac Cardiovasc Surg. 2020 May;159(5):2003-2007. doi: 10.1016/j.jtcvs.2019.08.128. Epub 2019 Sep 23.

Authors

Boyang Zhang¹, Milica Radisic²

Affiliations

¹ Department of Chemical Engineering, McMaster University, Hamilton, Ontario, Canada; School of Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada. Electronic address: zhangb97@mcmaster.ca.
² Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada; Institute for Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada; Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada; The Heart and Stroke/Richard Lewar Centre of Excellence, Toronto, Ontario, Canada. Electronic address: m.radisic@utoronto.ca.

PMID: 31668537
DOI: 10.1016/j.jtcvs.2019.08.128

Abstract

Organ-level vascularization has been a long-standing challenge in the field of tissue engineering. Recent advances, particularly in the use of projection stereolithography and food colors as photoabsorbers are highlighted, as are several recent studies on the clinical translation of engineered vasculature.

Publication types

Editorial

MeSH terms

Animals
Humans
Mice
Neovascularization, Physiologic*
Tissue Engineering*
Transplants / blood supply*