Sustained Monomorphic Ventricular Tachycardia in Nonischemic Heart Disease: Arrhythmia-Substrate Correlations That Inform the Approach to Ablation

Circ Arrhythm Electrophysiol. 2019 Nov;12(11):e007312. doi: 10.1161/CIRCEP.119.007312. Epub 2019 Oct 30.

Abstract

As the population of patients with implanted defibrillators has grown, an increasing number of patients nonischemic cardiomyopathies are requiring therapy to reduce ventricular arrhythmias. Most of these arrhythmias are related to areas of ventricular scar. Although the pathophysiology of scar development is not well understood in these diseases, advances in cardiac imaging and mapping are better characterizing the scar locations that give rise to the arrhythmias. Here, we review the pathophysiologic and electrocardiographic correlations that inform ablation strategies for ventricular tachycardia in these diseases.

Keywords: ablation; arrhythmia; cardiomyopathies; defibrillators; tachycardia.

Publication types

  • Review

MeSH terms

  • Cardiomyopathies / complications*
  • Cardiomyopathies / diagnosis
  • Cardiomyopathies / physiopathology
  • Catheter Ablation / methods*
  • Diagnostic Techniques, Cardiovascular*
  • Electrocardiography
  • Heart Ventricles / diagnostic imaging
  • Heart Ventricles / physiopathology*
  • Humans
  • Tachycardia, Ventricular / diagnosis
  • Tachycardia, Ventricular / etiology*
  • Tachycardia, Ventricular / surgery
  • Ventricular Function, Left / physiology*