Clinical ResearchDifferential Regulation of ANP and BNP in Acute Decompensated Heart Failure: Deficiency of ANP
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Central Illustration
Key Words
acute decompensated heart failure
atrial natriuretic peptide deficiency
atrial natriuretic peptide
natriuretic peptide
Abbreviations and Acronyms
ADHF
acute decompensated heart failure
ANP
atrial natriuretic peptide
BMI
body mass index
BNP
B-type natriuretic peptide
cGMP
3′,5′cyclic guanosine monophosphate
EF
ejection fraction
eGFR
estimated glomerular filtration rate
HFpEF
heart failure with preserved ejection fraction
HFrEF
heart failure with reduced ejection fraction
NP
natriuretic peptide
pGC-A
particulate guanylyl cyclase A receptor
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Supported by National Heart, Lung and Blood Institute grants R01 HL36634 and RO1 HL13688 to Dr. Burnett and by the Mayo Foundation. Dr. Burnett holds equity in a patent licensed to Zumbro Discovery; and is consultant to Novartis and Ironwood. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
© 2019 by the American College of Cardiology Foundation. Published by Elsevier.