Focus Issue: Developing Therapies in Heart Failure: A New Era for Drugs and DevicesClinical ResearchAssociation Between Sacubitril/Valsartan Initiation and Health Status Outcomes in Heart Failure With Reduced Ejection Fraction
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The CHAMP-HF and the present study were funded by the Novartis Pharmaceuticals Corp. Drs. Khariton and Nassif are supported by U.S. National Heart, Lung, and Blood Institutes award T32HL110837. The content is solely the responsibility of the authors and does not necessarily represent the official views of the U.S. National Institutes of Health (NIH). Dr. Sharma was an employee of Novartis at the time of the development and review of this paper. Dr. Spertus has received research support from National Institute of Health (NIH), American College of Cardiology Foundation, Bayer, Novartis, and Abbott Vascular; serves on a Scientific Advisory Board for United Healthcare; is a consultant for Novartis, V-Wave, AstraZeneca, Janssen, Corvia, and Bayer; holds patent rights to the Kansas City Cardiomyopathy Questionnaire; and holds equity in Health Outcomes Sciences. Dr. Thomas has received research support from Novartis Pharmaceuticals Corp. Dr. Fonarow has received research support from NIH; and is a consultant for Abbott, Amgen, Bayer, Janssen, Medtronic, and Novartis. Dr. DeVore has received research support from the American Heart Association, Amgen, NIH, and Novartis; and is a consultant for Novartis. Dr. Butler has received research support from NIH and European Union; and is a consultant for Amgen, Bayer, Boehringer Ingelheim, Cardiocell, CVRx, Gilead, Janssen, Medtronic, Merck, Novartis, Relypsa, and ZS Pharma. Dr. Albert is a consultant for Novartis, AstraZeneca, and Boston Scientific; and has received honoraria from Novartis. Dr. Patterson has received consulting and research support for Novartis. Drs. Duffy and McCague are employees of Novartis. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.