Atherosclerotic cardiovascular disease and heart failure: Determinants of risk and outcomes in patients with diabetes

Prog Cardiovasc Dis. 2019 Jul-Aug;62(4):306-314. doi: 10.1016/j.pcad.2019.07.001. Epub 2019 Jul 10.

Abstract

Cardiovascular disease (CVD) is the most common cause of morbidity and mortality for patients with diabetes mellitus (DM). Although the burden of atherosclerotic CVD (ASCVD) is well documented, heart failure (HF) has been an under-appreciated CVD complication of DM. However, as more patients with DM live longer and survive acute ASCVD events, the distribution of CVD complications has evolved. This review summarizes the epidemiology of DM, the relative risk and prognosis of both ASCVD and HF following a diagnosis of DM, and the likelihood of cause-specific CVD mortality in patients with DM.

Keywords: Atherosclerotic cardiovascular disease; Diabetes; Heart failure; Risk.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Aged
  • Atherosclerosis / diagnosis
  • Atherosclerosis / epidemiology*
  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / epidemiology*
  • Cause of Death*
  • Comorbidity
  • Diabetes Mellitus / diagnosis
  • Diabetes Mellitus / epidemiology*
  • Female
  • Heart Failure / diagnosis
  • Heart Failure / epidemiology*
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Severity of Illness Index
  • Survival Analysis
  • United States / epidemiology