Case reports of coronary fibromuscular dysplasia and spontaneous coronary artery dissections

Catheter Cardiovasc Interv. 2019 Mar 1;93(4):631-634. doi: 10.1002/ccd.27982. Epub 2018 Nov 23.

Abstract

Spontaneous coronary artery dissection (SCAD) is an important cause of acute coronary syndrome especially in women. The most common underlying predisposing cause of SCAD is fibromuscular dysplasia (FMD), a non-inflammatory arteriopathy that results in weakening of the affected arteries, and can cause dissection or aneurysm. Coronary FMD (CFMD) was described as rare, and was shown to cause SCAD in histopathological case reports. Unfortunately, CFMD is challenging to diagnose on coronary angiography, as the findings can be similar to other causes of coronary artery disease. Therefore, we illustrate two case examples of CFMD on coronary angiography, and highlight findings on optical coherence tomography to aid diagnosis.

Keywords: fibromuscular dysplasia (FMD); myocardial infarction; spontaneous coronary artery dissection (SCAD).

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Coronary Angiography*
  • Coronary Vessel Anomalies / diagnostic imaging*
  • Coronary Vessel Anomalies / etiology
  • Coronary Vessel Anomalies / pathology
  • Coronary Vessel Anomalies / therapy
  • Coronary Vessels / diagnostic imaging*
  • Coronary Vessels / pathology
  • Female
  • Fibromuscular Dysplasia / complications
  • Fibromuscular Dysplasia / diagnostic imaging*
  • Fibromuscular Dysplasia / pathology
  • Fibromuscular Dysplasia / therapy
  • Humans
  • Male
  • Predictive Value of Tests
  • Tomography, Optical Coherence*
  • Vascular Diseases / congenital*
  • Vascular Diseases / diagnostic imaging
  • Vascular Diseases / etiology
  • Vascular Diseases / pathology
  • Vascular Diseases / therapy

Supplementary concepts

  • Coronary Artery Dissection, Spontaneous