Catheter ablation of atrial fibrillation in heart failure with reduced ejection fraction

J Cardiovasc Electrophysiol. 2018 Jul;29(7):1049-1058. doi: 10.1111/jce.13497. Epub 2018 Apr 23.

Abstract

Atrial fibrillation and heart failure are increasing in prevalence, and frequently coexist. Despite the desire to restore sinus rhythm in heart failure patients, large studies comparing rate control to pharmacologic rhythm control have failed to show superiority of either approach. This may in part be due to the inefficacy and higher risk of adverse effects with antiarrhythmic drugs in HF patients. As such, catheter ablation for atrial fibrillation in patients with heart failure with reduced ejection fraction has been increasingly explored as a treatment modality. We review the contemporary evidence regarding patient selection, efficacy, safety, and impact of catheter ablation on outcomes in patients with atrial fibrillation and heart failure with reduced ejection fraction.

Keywords: atrial fibrillation; catheter ablation; heart failure; outcomes; review.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Atrial Fibrillation / epidemiology
  • Atrial Fibrillation / physiopathology*
  • Atrial Fibrillation / surgery*
  • Catheter Ablation / methods*
  • Heart Failure / epidemiology
  • Heart Failure / physiopathology*
  • Heart Failure / surgery*
  • Humans
  • Randomized Controlled Trials as Topic / methods
  • Stroke Volume / physiology*