Preventive CardiologyGender-Related Cardiovascular Risk in Healthy Middle-Aged Adults
Section snippets
Methods
The Institute for Medical Screening at the Chaim Sheba Medical Center has annual screening program for executives, which performs about 10,000 screening examinations each year. All participants are self-referred asymptomatic men and women. Most participants have repeated annual visits for a number of years. This database is well suited for the characterization, follow-up, and clinical event identification of asymptomatic population.
A computerized database was established in the year 2000 and
Results
Among 14,966 study subjects, 4,442 (29%) were women. All participants were between 21 to 91 years old, mean age was 46.98 years (median age was 46 years; interquartile range 40 to 53). Baseline characteristics of the study populations by gender are presented in Table 1. Compared with men, women were younger, had lower baseline systolic blood pressure, had lower rates of obesity and impaired fasting glucose, and had a significantly better baseline lipid profile (all p value <0.001). Women's
Discussion
In the present study, we aimed to evaluate whether an independent gender difference exists regarding CVD risk in a large cohort of apparently healthy middle-aged adults. Our findings suggest that there is an independent gender difference in CVD risk between men and women and that traditional risk factors profiles cannot fully account for this risk difference. In our study, we included healthy subjects without co-morbidities such as hypertension or diabetes mellitus. This population was selected
Disclosures
The authors have no conflicts of interest to disclose.
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This work was supported by the Shalvi Foundation for Medical Research.
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