Clinical and procedural characteristics associated with higher radiation exposure during percutaneous coronary interventions and coronary angiography

Circ Cardiovasc Interv. 2013 Oct 1;6(5):501-6. doi: 10.1161/CIRCINTERVENTIONS.113.000220. Epub 2013 Sep 24.

Abstract

Background: We aim to study the clinical and procedural characteristics associated with higher radiation exposure in patients undergoing percutaneous coronary interventions (PCIs) and coronary angiography.

Methods and results: Our present study included all coronary angiography and PCI procedures in 5 PCI centers in the Western part of Sweden, between January 1, 2008, and January 19, 2012. The radiation exposure and clinical data were collected prospectively in these 5 PCI centers in Sweden as part of the Swedish Coronary Angiography and Angioplasty Registry (SCAAR). A prediction model was made for the radiation exposure (dose-area product) expressed in Gy·cm(2). A total of 20 669 procedures were included in the present study, consisting of 9850 PCI and 10 819 coronary angiography procedures. In multivariable analyses, body mass index (β=1.04; confidence interval [CI], 1.04-1.04; P<0.001); history of coronary artery bypass graft surgery (β=1.32; CI, 1.28-1.32; P<0.001); 2, 3, or 4 treated lesions (2 treated lesions: β=1.95; CI, 1.84-2.03; P<0.001; 3 treated lesions: β=2.34; CI, 2.16-2.53; P<0.001; and 4 treated lesions: β=2.83; CI, 2.53-3.16; P<0.001); and chronic total occlusion lesions (β=1.39; CI, 1.31-1.48; P<0.001) were associated with the highest radiation exposure. After adjusting for procedural complexity, radial access route was not associated with increased radiation exposure (β=1.00; CI, 0.98-1.03; P=0.67).

Conclusions: In the largest study population to assess radiation exposure, we found that high body mass index, history of coronary artery bypass graft surgery, number of treated lesions, and chronic total occlusions were associated with the highest patient radiation exposure. Radial access site was not associated with higher radiation exposure when compared with femoral approach.

Keywords: fluoroscopy; percutaneous coronary intervention; radiation.

Publication types

  • Multicenter Study

MeSH terms

  • Aged
  • Body Mass Index
  • Coronary Angiography / adverse effects
  • Coronary Angiography / statistics & numerical data*
  • Coronary Artery Bypass
  • Coronary Occlusion
  • Female
  • Humans
  • Male
  • Middle Aged
  • Models, Theoretical
  • Neoplasms, Radiation-Induced / epidemiology*
  • Neoplasms, Radiation-Induced / etiology
  • Percutaneous Coronary Intervention / adverse effects*
  • Percutaneous Coronary Intervention / statistics & numerical data*
  • Prognosis
  • Radial Artery / surgery
  • Radiation Injuries / epidemiology*
  • Radiation Injuries / etiology
  • Radiometry
  • Risk Factors
  • Sweden