Elsevier

Journal of Cardiac Failure

Volume 29, Issue 11, November 2023, Pages 1522-1530
Journal of Cardiac Failure

Fewer Worsening Heart Failure Events With HeartLogic on top of Standard Care: a Propensity-Matched Cohort Analysis

https://doi.org/10.1016/j.cardfail.2023.04.012Get rights and content
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open access

Highlights

  • Early detection of congestion is essential to prevent hospitalizations due to heart failure.

  • The HeartLogic algorithm can detect impending fluid retention.

  • Activating HeartLogic is associated with fewer worsening heart failure events.

  • Patients with an activated HeartLogic algorithm are hospitalized for shorter times.

ABSTRACT

Background

The implantable cardiac defibrillator-based HeartLogic algorithm aims to detect impending fluid retention in patients with heart failure (HF). Studies show that HeartLogic is safe to integrate into clinical practice. The current study investigates whether HeartLogic provides clinical benefit on top of standard care and device telemonitoring in patients with HF.

Methods

A multicenter, retrospective, propensity-matched cohort analysis was performed in patients with HF and implantable cardiac defibrillators, and it compared HeartLogic to conventional telemonitoring. The primary endpoint was the number of worsening HF events. Hospitalizations and ambulatory visits due to HF were also evaluated.

Results

Propensity score matching yielded 127 pairs (median age 68 years, 80% male). Worsening HF events occurred more frequently in the control group (2; IQR 0–4) compared to the HeartLogic group (1; IQR 0–3; P = 0.004). The number of HF hospitalization days was higher in controls than in the HeartLogic group (8; IQR 5–12 vs 5; IQR 2–7; P = 0.023), and ambulatory visits for diuretic escalation were more frequent in the control group than in the HeartLogic group (2; IQR 0–3 vs 1; IQR 0–2; P = 0.0001).

Conclusion

Integrating the HeartLogic algorithm in a well-equipped HF care path on top of standard care is associated with fewer worsening HF events and shorter duration of fluid retention-related hospitalizations.

Key Words

chronic heart failure
ICD
remote monitoring
heart failure hospitalization

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