Transient fetal atrioventricular block: A series of four cases and approach to management

J Cardiovasc Electrophysiol. 2022 Oct;33(10):2228-2232. doi: 10.1111/jce.15642. Epub 2022 Sep 1.

Abstract

Introduction: Fetal atrioventricular block (AVB) is a failure of conduction from atria to ventricles. Immune- and nonimmune-mediated forms occur, especially in association with congenital heart disease. Second-degree (2°) AVB may be reversible with dexamethasone and intravenous immunoglobulin in immune-mediated disease. However, once third-degree AVB develops, it is deemed irreversible with need for a pacemaker and risk for cardiomyopathy. Rarely, 2° AVB is a transient, benign phenomenon in the immature conduction system. Few case series of transient AVB have been reported, but a management approach has not been defined.

Methods/results/conclusion: We report four patients with self-resolving, nonimmune fetal AVB and outline a management strategy.

Keywords: fetal atrioventricular block; fetal heart block; fetal second-degree atrioventricular block; long QT syndrome.

Publication types

  • Case Reports

MeSH terms

  • Atrioventricular Block* / diagnosis
  • Atrioventricular Block* / etiology
  • Atrioventricular Block* / therapy
  • Dexamethasone / therapeutic use
  • Heart Conduction System
  • Heart Rate
  • Humans
  • Immunoglobulins, Intravenous

Substances

  • Immunoglobulins, Intravenous
  • Dexamethasone