Clinical ResearchTolerability of Sacubitril/Valsartan in Patients With Advanced Heart Failure: Analysis of the LIFE Trial Run-In
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Central Illustration
Key Words
advanced heart failure
guideline-directed medical therapy
New York Heart Association class IV
sacubitril/valsartan
tolerability
Abbreviations and Acronyms
ACEI
angiotensin-converting enzyme inhibitor
ARB
angiotensin receptor blocker
CRT-D
cardiac resynchronization therapy-defibrillator
HF
heart failure
ICD
implantable cardioverter-defibrillator
MAP
mean arterial blood pressure
NT-proBNP
N-terminal pro–B-type natriuretic peptide
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© 2022 the American College of Cardiology Foundation. Published by Elsevier.