We searched MEDLINE and Embase for articles published between June 1, 2015, and Jan 31, 2021, using the indexed terms “suicide” and “self-harm” in combination with section specific terms, which included “epidemiology”, “risk factors”, “prevention”, and “intervention”. We gave precedence to publications within the past 5 years and systematic reviews identified through these searches. We do, however, also reference highly cited older publications. Relevant contemporary review articles and book
SeminarSuicide and self-harm
Introduction
Data from WHO suggest that, globally, suicide accounts for at least 700 000 deaths per year. The actual number is likely to be much higher because of under-recording. Suicide has become a defining health and societal issue in many countries.1 Self-harm (self-poisoning or self-injury with varying degrees of suicidal intent) is even more common, with an estimated 14·6 million individuals affected each year.2 Suicide has received a great deal of attention during the COVID-19 public health emergency,3 and its prevention will continue to be a priority as we move into subsequent phases and eventual recovery from the pandemic.
Many people who die by suicide have a history of self-harm, and previous self-harm is the strongest risk factor for suicide, at least in high-income settings.4 Despite suicide and self-harm sometimes being seen as distinct concepts, here we discuss them together, given that many of the principles of intervention and prevention are common to both.
Suicide and self-harm are intensely individual experiences that are often markers of unbearable psychological pain; however, suicide and self-harm are also affected by societal factors. It has been known for at least a century that economic adversity is associated with higher suicide rates. Clinicians need to be at the forefront of suicide prevention efforts, because policy makers and the public will look towards clinicians for leadership, particularly in low-income and middle-income countries (LMICs). Public health factors need to be recognised, and the role of mental and physical health must also be acknowledged—a proportion of people who die by suicide have a psychiatric disorder at the time of death, and many, particularly in older age groups (eg, those older than 65 years), have a physical illness.5, 6 Most of these individuals, at least in high-income settings, will have consulted health services in the year before they die,7 some having harmed themselves. Each clinical encounter should be seen as an opportunity to intervene.
Stigma remains a serious issue in clinical and non-clinical settings, and the language we use is important. Suicide might not be openly discussed, or might even be perceived as a selfish act. Many people who self-harm have a poor experience of health care: “In many cases, staff lacked compassion. Such as invalidating my distress, stigmatising responses such as ‘wow you really meant to kill yourself, didn't you!!', exclaiming at the severity of my previous scarring and saying I was ‘adding to the collection', saying that my pain threshold must be high and deciding not to give me any pain relief or medications when stitching or cleaning wounds (almost as if it was to be a punishment for self-harming), saying that I was ‘wasting time' and other people had ‘real' injuries.”8
Patients report that clinicians might blame them or deny them access to high quality care because of the erroneous belief that providing good care will encourage future episodes. Such attitudes might be partly related to a lack of knowledge and understanding. Clinicians also need to be aware that some individuals view their self-harm as a coping strategy to manage psychological distress or even prevent suicide.
In this Seminar we aim to provide an update on suicide and self-harm with a global and practical focus. We also discuss current and emerging issues. Further discussion of the terminology used throughout the Seminar and the importance of language are included in the appendix (pp 2–3).
Section snippets
Suicide
One person dies by suicide every 40 seconds,9 and for every person who dies, 60–135 people are affected by the death.10 The global rate of suicide is estimated to be 9·4 per 100 000 people (95% CI 8·5–10·3), with higher rates in male individuals (13·3 per 100 000 [11·3–14·7]) than female individuals (5·7 per 100 000 [5·1–6·4]).2 Possible explanations for higher rates in male individuals include methods of suicide (they might choose more dangerous methods with a higher case fatality than female
Risk factors
When someone dies by suicide or harms themselves, the most common question asked is why did it happen? Families, friends, and sometimes even the person who has harmed themselves might look to clinicians for answers. These answers are typically difficult to give. Suicide and self-harm are complex and never the result of a single cause. Many of the risk factors are non-specific and apply to suicide, self-harm, and psychological distress. Although it is useful for clinicians to have a broad
Clinical assessment
Following an incident of self-harm, a sensitively conducted assessment that pays close attention to establishing rapport can be therapeutic for patients.55 Patients emphasise the importance of feeling listened to, and these assessments can lead to better engagement with future treatment. Although evidence on the benefits of assessment is mostly focused on self-harm, many of the same principles will apply to patients presenting with suicidal thoughts. Confidentiality is an important issue, but
Psychological interventions
Research suggests psychological interventions might be effective in preventing self-harm and suicide,82, 83 although current evidence has substantial methodological limitations and is limited to HICs. Cognitive behavioural therapy and related treatments have the strongest evidence base for reducing suicidal ideation and repeat self-harm compared with treatment as usual.82 Dialectical behavioural therapy, an intensive psychological intervention that incorporates principles of cognitive
Conclusion
Suicide is an individual tragedy as well as a global concern. Suicide prevention must encompass both a clinical and societal focus. Every health professional has a crucial part to play, whether by sensitively assessing or treating self-harm, or advocating for the implementation of suicide prevention measures. Current and emerging threats, such as the COVID-19 pandemic, migration, and climate change, will have an effect on suicide and self-harm. Ageing populations, the use of data and new
Search strategy and selection criteria
Declaration of interests
DK is funded through the Elizabeth Blackwell Institute for Health Research at the University of Bristol, which is supported by the Wellcome Trust. DK is also in receipt of a grant from the Centre for Pesticide Suicide Prevention. PP's PhD clinical fellowship is funded by the UK Medical Research Council Addiction Research Clinical Training programme, grant number MR/N00616X/1. PP is also in receipt of a grant from Bristol and Weston Hospitals Charity. LFC declares receiving funding from Johnson
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