Transcatheter Mitral Valve Implantation In Patients With Chronic Kidney Disease
Section snippets
Methods
This retrospective cohort study used data from the Nationwide Readmissions Database (NRD). The NRD is the largest publicly available all-payer inpatient readmission database in the United States. Unweighted, it contains approximately 18 million annual discharges from 28 states in the United States; weighted, it comprises roughly 35 million annual discharges, accounting for 58.7% of all United States hospitalizations and 59.7% of the total United States population. Patients are identified and
Results
From 2015 to 2018, there were 2,066 discharge records for patients receiving TS-TMVI. After excluding records with missing vital status (n = 3) and records with CKD stages I to II (n = 46), the final analysis included 2,017 records. Of these hospitalizations, 733 (36.34%) had CKD, and 1,284 (63.66%) did not have CKD. In the CKD group, 76 (10.4%) required chronic dialysis. During the study years, there was an increase in the uptake of TS-TMVI in patients with CKD (11 in 2015 vs 346 in 2018, p
Discussion
In the present analysis including 2,017 hospitalized patients for TS-TMVI, we evaluated the comparative short-term outcomes in those with versus without CKD. The salient study findings are as follows: (1) there was an increase in the use of TS-TMVI procedures in those with CKD during the study years; (2) there was no significant difference in in-hospital mortality after TS-TMVI in those with versus without CKD; (3) TS-TMVI in patients with CKD was associated with higher rates of cardiogenic
Disclosures
The authors have no conflicts of interest to declare.
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