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Correction: Immunogenicity and reactogenicity of SARS-CoV-2 vaccines in people living with HIV in the Netherlands: A nationwide prospective cohort study

  • Kathryn S. Hensley,
  • Marlou J. Jongkees,
  • Daryl Geers,
  • Corine H. GeurtsvanKessel,
  • Yvonne M. Mueller,
  • Virgil A. S. H. Dalm,
  • Grigorios Papageorgiou,
  • Hanka Steggink,
  • Alicja Gorska,
  • Susanne Bogers,
  • Jan G. den Hollander,
  • Wouter F. W. Bierman,
  • Luc B. S. Gelinck,
  • Emile F. Schippers,
  • Heidi S. M. Ammerlaan,
  • Marc van der Valk,
  • Marit G. A. van Vonderen,
  • Corine E. Delsing,
  • Elisabeth H. Gisolf,
  • Anke H. W. Bruns,
  • Fanny N. Lauw,
  • Marvin A. H. Berrevoets,
  • Kim C. E. Sigaloff,
  • Robert Soetekouw,
  • Judith Branger,
  • Quirijn de Mast,
  • Adriana J. J. Lammers,
  • Selwyn H. Lowe,
  • Rory D. de Vries,
  • Peter D. Katsikis,
  • Bart J. A. Rijnders,
  • Kees Brinkman,
  • Anna H. E. Roukens,
  •  [ ... ],
  • Casper Rokx
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Fig 3 panel B contains a mislabeled axis. The label ‘Pre—HIV negative’ should be ‘Post—HIV negative.’ Please see the correct Fig 3 below.

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Fig 3. Cellular immune responses against SARS-CoV-2 in subgroup participants (PLWH).

(A) Cellular immune response to wild-type spike by ELISpot assay (Pre, n = 23; Post, n = 45): IFN-γ SFCs after subtraction of MOG. Statistics performed using Mann–Whitney U test: p = 0.002. Negative responses: Pre, 8; Post, 5. (B) Cellular immune response to wild-type and Delta spike in AIM assay (n = 14): percentage of CD4+ CD137+ OX40+ T-cells after subtraction of DMSO. Dotted line shows the LLoD at 0.001%. Statistics between pre- and post-vaccination for WT in PLWH performed using Wilcoxon matched-pairs signed rank test (p = 0.005); pre- and post-vaccination for Delta: ns. Statistics between PLWH and controls with Mann–Whitney U test: not significant. (C) Cellular immune response to wild-type and Delta spike in AIM assay (n = 14): percentage of CD8+ CD137+ CD69+ T-cells after subtraction of DMSO. Dotted line shows the LLoD at 0.001%. Statistics performed using Wilcoxon matched-pairs signed rank test (p = 0.008); pre- and post-vaccination for Delta: ns. Statistics between PLWH and controls with Mann–Whitney U test: not significant. Green circles: mRNA vaccines; blue squares: vector-based vaccines. Pre: before vaccination; Post: 4–6 weeks after second vaccination. AIM, activation-induced marker; BAU, binding antibody units; cART, combination antiretroviral therapy; DMSO, dimethyl sulfoxide; ELISpot, enzyme-linked immune absorbent spot; GMC, geometric mean concentration; INF-γ, interferon-γ; LLoD, lower limit of detection; MOG, myelin oligodendrocyte glycoprotein; PBMC, peripheral blood mononuclear cell; PLWH, people living with HIV; SFC, spot-forming cell; WT, wild type.

https://doi.org/10.1371/journal.pmed.1004159.g001

Reference

  1. 1. Hensley KS, Jongkees MJ, Geers D, GeurtsvanKessel CH, Mueller YM, Dalm VASH, et al. (2022) Immunogenicity and reactogenicity of SARS-CoV-2 vaccines in people living with HIV in the Netherlands: A nationwide prospective cohort study. PLoS Med 19(10): e1003979. https://doi.org/10.1371/journal.pmed.1003979 pmid:36301821