Clinical ResearchIGFBP-7 and Outcomes in Heart Failure With Reduced Ejection Fraction: Findings From DAPA-HF
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Central Illustration
Key Words
biomarker
dapagliflozin
heart failure
insulin-like growth factor–binding protein-7
SGLT2 inhibitor
Abbreviations and Acronyms
CV
cardiovascular
eGFR
estimated glomerular filtration rate
HF
heart failure
HFpEF
heart failure with preserved ejection fraction
HFrEF
heart failure with reduced ejection fraction
hsTnT
high-sensitivity troponin T
IGFBP
insulin-like growth factor–binding protein
LVEF
left ventricular ejection fraction
NRI
net reclassification index
NT-proBNP
N-terminal pro–B-type natriuretic peptide
SBP
systolic blood pressure
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Barry Greenberg, MD, served as the Guest Editor-in-Chief for this paper.
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© 2022 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.