Clinical ResearchHemodynamically-Guided Management of Heart Failure Across the Ejection Fraction Spectrum: The GUIDE-HF Trial
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Central Illustration
Key Words
ejection fraction
heart failure
hemodynamics
pulmonary artery pressure
Abbreviations and Acronyms
ACE
angiotensin-converting enzyme
AE
adverse event
ARB
angiotensin receptor blocker
ARNI
angiotensin receptor blocker-neprilysin inhibitor
EF
ejection fraction
FDA
Food and Drug Administration
HF
heart failure
HFmrEF
heart failure with mildly reduced ejection fraction
HFpEF
heart failure with preserved ejection fraction
HFrEF
heart failure with reduced ejection fraction
MRA
mineralocorticoid receptor antagonist
NYHA
New York Heart Association
PA
pulmonary artery
SAP
statistical analysis plan
SGLT2
sodium-glucose transport protein 2
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G. Michael Felker, MD, served as Guest Associate Editor for this paper. Barry Greenberg, MD, served as Guest Editor-in-Chief for this paper.
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© 2022 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.