Original InvestigationMyosin Inhibition in Patients With Obstructive Hypertrophic Cardiomyopathy Referred for Septal Reduction Therapy
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Central Illustration
Key Words
mavacamten
obstructive HCM
randomized clinical trial
septal reduction
Abbreviations and Acronyms
C5Research
Cleveland Clinic Coordinating Center for Clinical Research
HCM
hypertrophic cardiomyopathy
iDMC
independent data monitoring committee
KCCQ-23 CSS
Kansas City Cardiomyopathy Questionnaire 23-item Clinical Summary Score
LTE
long-term extension
LV
left ventricular
LVOT
left ventricular outflow tract
NT-proBNP
N-terminal pro–B-type natriuretic peptide
NYHA
New York Heart Association
oHCM
obstructive hypertrophic cardiomyopathy
SRT
septal reduction therapy
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