High-Burden Premature Atrial Contractions Predict New-Onset Atrial Fibrillation After Surgical Septal Myectomy
Section snippets
Methods
From January 2015 to December 2018, a total of 695 patients with OHCM consecutively admitted at our institution underwent septal myectomy. We excluded 55 patients with preoperative AF history, 291 patients with other cardiac surgeries, 29 patients without a 24-hour Holter electrocardiogram, 16 patients with preoperative permanent pacemaker installation and ventricular septal ablation, and 304 consecutively admitted patients who underwent isolated septal myectomy (Figure 1). According to the
Results
Data on baseline characteristics of the entire population classified by PAC numbers are listed in Table 1. All patients recovered well during the perioperative period without major complications. A total of 304 consecutively admitted patients with OHCM (183 men, 60.20%; median age: 47 years) were included in the study. Of these, 45 patients (14.80%) had no PACs and 259 patients (85.20%) had PACs. Patients were divided into low-PAC-burden (n = 211, 69.41%) and high PAC burden (n = 48, 15.79%)
Discussion
There are relatively few studies on the relation between PACs in preoperative 24-hour Holter monitoring and POAF after cardiac surgery, particularly in patients with OHCM with left ventricular diastolic insufficiency. In this study, we investigated the correlation between preoperative PACs with different burdens and POAF in patients with OHCM who underwent isolated septal myectomy. The main findings of this study were as follows: first, PAC incidence was high (85%) in patients with OHCM without
Disclosures
The authors have no conflicts of interest to declare.
Acknowledgment
The authors would like to thank Editage (http://www.editage.cn) for English language editing.
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Cited by (0)
Drs. Meng and Nie contributed equally to this work and share first authorship.
Funding: This work was supported by the Chinese National High Level Hospital Clinical Research Funding, 2022-GSP-GG-29 and Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences, Beijing, China, 2022-I2M-1-005.