Transcatheter Patent Foramen Ovale Closure in Patients With Transient Ischemic Attack
Section snippets
Methods
This was a study including consecutive patients who had transcatheter PFO closure after a cryptogenic thromboembolic event between 2001 and 2020 in 2 high-volume tertiary-care University centers in Canada and France.
Patients were divided into 2 groups according to their primary PFO-related event (stroke or TIA). The stroke diagnosis was confirmed with either computed tomography (CT) or magnetic resonance imaging (MRI) of the brain. The diagnosis of TIA was made following its previously
Results
Of 1,136 consecutive patients who underwent PFO closure, 124 (11%) had indications other than stroke or TIA and were excluded. Of the remaining 1,012 patients, 183 (18%) and 829 (82%) patients had transcatheter PFO closure because of a TIA and a stroke event, respectively. The baseline characteristics of both groups are summarized in Table 1. There were no significant differences between patients with TIA and stroke, except for a lower Risk of Paradoxical Embolism (RoPE) score in the TIA group
Discussion
The main findings of this study can be summarized as follows: (1) patients with a diagnosis of cryptogenic TIA presented the same clinical profile as those with stroke except for a slightly lower RoPE score, (2) transcatheter PFO closure was a safe procedure for patients with a PFO-related TIA, as shown by the low rate of procedural complications and the success rate of 100%, and (3) transcatheter PFO closure in patients with a PFO-related TIA may be effective as in patients with a PFO-related
Acknowledgment
Dr. Rodés-Cabau holds the Research Chair “Fondation Famille Jacques Larivière” for the Development of Structural Heart Disease Interventions.
Disclosures
The authors have conflicts of interest to declare.
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Funding: none.