In older patients receiving aspirin, H pylori eradication reduced hospitalization or death due to peptic ulcer bleeding at 2.5 y

Abhilash Perisetti; Prateek Sharma

doi:10.7326/J23-0011

In older patients receiving aspirin, H pylori eradication reduced hospitalization or death due to peptic ulcer bleeding at 2.5 y

Ann Intern Med. 2023 Apr;176(4):JC45. doi: 10.7326/J23-0011. Epub 2023 Apr 4.

Authors

Abhilash Perisetti¹, Prateek Sharma¹

Affiliation

¹ Kansas City Veterans Affairs Medical Center, Kansas City, Missouri, USA (A.P., P.S.).

PMID: 37011389
DOI: 10.7326/J23-0011

Abstract

Hawkey C, Avery A, Coupland CAC, et al; HEAT trialists. Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT): a randomised, double-blind, placebo-controlled trial. Lancet. 2022;400:1597-1606. 36335970.

Publication types

Randomized Controlled Trial
Comment

MeSH terms

Aged
Aspirin / adverse effects
Helicobacter Infections* / complications
Helicobacter Infections* / drug therapy
Helicobacter pylori*
Hospitalization
Humans
Peptic Ulcer Hemorrhage / prevention & control
Peptic Ulcer* / drug therapy
Peptic Ulcer* / prevention & control

Substances

Aspirin