SGLT2 inhibitors reduce adverse renal and CV outcomes in patients with or without diabetes

Ann Intern Med. 2023 Mar;176(3):JC27. doi: 10.7326/J23-0002. Epub 2023 Mar 7.

Abstract

Nuffield Department of Population Health Renal Studies Group; SGLT2 inhibitor Meta-Analysis Cardio-Renal Trialists' Consortium. Impact of diabetes on the effects of sodium glucose co-transporter-2 inhibitors on kidney outcomes: collaborative meta-analysis of large placebo-controlled trials. Lancet. 2022;400:1788-801. 36351458.

Publication types

  • Meta-Analysis
  • Comment

MeSH terms

  • Diabetes Mellitus, Type 2* / complications
  • Diabetes Mellitus, Type 2* / drug therapy
  • Heart
  • Humans
  • Hypoglycemic Agents / adverse effects
  • Kidney
  • Sodium-Glucose Transporter 2 Inhibitors* / therapeutic use

Substances

  • Sodium-Glucose Transporter 2 Inhibitors
  • Hypoglycemic Agents