In glucocorticoid-dependent polymyalgia rheumatica, tocilizumab improved a composite clinical outcome at 24 wk

Ann Intern Med. 2023 Jan;176(1):JC5. doi: 10.7326/J22-0107. Epub 2023 Jan 3.

Abstract

Devauchelle-Pensec V, Carvajal-Alegria G, Dernis E, et al. Effect of tocilizumab on disease activity in patients with active polymyalgia rheumatica receiving glucocorticoid therapy: a randomized clinical trial. JAMA. 2022;328:1053-62. 36125471.

Publication types

  • Randomized Controlled Trial
  • Comment

MeSH terms

  • Antibodies, Monoclonal, Humanized / adverse effects
  • Giant Cell Arteritis* / chemically induced
  • Giant Cell Arteritis* / drug therapy
  • Glucocorticoids / therapeutic use
  • Humans
  • Polymyalgia Rheumatica* / drug therapy

Substances

  • Glucocorticoids
  • tocilizumab
  • Antibodies, Monoclonal, Humanized