Dietary management of dyslipidemia and the impact of dietary patterns on lipid disorders

Prog Cardiovasc Dis. 2022 Nov-Dec:75:49-58. doi: 10.1016/j.pcad.2022.11.003. Epub 2022 Nov 19.

Abstract

Dyslipidemia is a major risk factor for atherosclerotic cardiovascular disease and a healthy lifestyle is the first line of therapy for treatment. A healthy dietary pattern is a cornerstone for treating elevated low-density lipoprotein-cholesterol (LDL-C) and triglycerides (TG), both of which are hallmarks of dyslipidemia. Much research has been conducted evaluating the effect of different dietary patterns on LDL-C and TG, both eucalorically and with weight loss. Herein we review studies that have evaluated the effects of different dietary patterns on LDL-C and TG. Within the context of a healthy dietary pattern, constituent food and nutrient intakes impact LDL-C and TG lowering. Food- and nutrient-based recommendations for lowering both LDL-C and TG, will also be reviewed. Finally, the suitability of popular diets for patients with dyslipidemia will be discussed. Lifestyle interventions, including dietary intervention, should be individualized and customized to patient preferences to achieve clinically relevant lipid/lipoprotein improvements.

Keywords: Dyslipidemia; Healthy dietary patterns; LDL-C; Triglycerides.

Publication types

  • Review

MeSH terms

  • Cholesterol
  • Cholesterol, HDL
  • Cholesterol, LDL
  • Diet / adverse effects
  • Dyslipidemias* / diagnosis
  • Dyslipidemias* / therapy
  • Humans
  • Triglycerides

Substances

  • Cholesterol, LDL
  • Triglycerides
  • Cholesterol
  • Cholesterol, HDL