In acute ischemic stroke, thrombectomy was not noninferior to alteplase + thrombectomy for 90-d functional independence

Ann Intern Med. 2022 Nov;175(11):JC125. doi: 10.7326/J22-0088. Epub 2022 Nov 1.

Abstract

Fischer U, Kaesmacher J, Strbian D, et al. Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial. Lancet. 2022;400:104-15. 35810756.

Publication types

  • Comment

MeSH terms

  • Equivalence Trials as Topic
  • Functional Status
  • Humans
  • Ischemic Stroke* / drug therapy
  • Ischemic Stroke* / surgery
  • Randomized Controlled Trials as Topic
  • Thrombectomy
  • Tissue Plasminogen Activator / therapeutic use
  • Treatment Outcome

Substances

  • Tissue Plasminogen Activator